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Product Name | Melanoma Inhibitory Activity (MIA) (Active) protein |
Description | MIA is the first discovered member of a family of secreted cytokines termed the MIA/OTOR family. The four known members of this family, MIA, MIA2, OTOR and TANGO each contain a Src homology-3 (SH3)-like domain. MIA is an autocrine growth regulatory protein secreted from chondrocytes and malignant melanoma cells that promotes melanoma metastasis by binding competitively to fibronectin and laminin in a manner that results in melanoma cell detachment from the extracellular matrix in vivo. Elevated levels of MIA may represent a clinically useful marker for diagnosis of melanoma metastasis as well as a potential marker for rheumatoid arthritis. Alternative Names: Cartilage-derived retinoic acid-sensitive protein protein, CD-RAP protein, Melanoma Inhibitory Activity protein |
Size | 100 µg |
Concentration | n/a |
Applications | n/a |
Other Names | zgc:194157|mia|CD-RAP|Mia1|Cdrap|CDRAP|Fdp|MIA|MIAL |
Gene, Accession, CAS # | Gene ID: 8190 |
Catalog # | ABIN2648118 |
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Order / More Info | Melanoma Inhibitory Activity (MIA) (Active) protein from ANTIBODIES-ONLINE GmbH |
Product Specific References | n/a |
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