| 产品详情 |
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| Product Name | Recombinant Human Nanos homolog 2 (NANOS2) |
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| Description | Purity > 90% as determined by SDS-PAGE. MW: 31.1kDa. Full Length: 1-138aa. N-terminal 6xHis-SUMO-tagged. Homo sapiens (Human). Plays a key role in the sexual differentiation of germ cells by promoting the male fate but suppressing the fale fate. Represses the fale fate pathways by suppressing meiosis, which in turn results in the promotion of the male fate. Maintains the suppression of meiosis by preventing STRA8 expression, which is required for preiotic DNA replication, after CYP26B1 is decreased. Regulates the localization of the CCR4-NOT deadenylation complex to P-bodies and plays a role in recruiting the complex to trigger the degradation of mRNAs involved in meiosis. Required for the maintenance of the spermatogonial st cell population. Not essential for the assbly of P-bodies but is required for the maintenance of their normal state. |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | RUO |
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| Other Names | n/a |
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| Gene, Accession, CAS # | NANOS2, UniProt: P60321 |
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| Catalog # | RPC21712 |
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| Price | |
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| Order / More Info | Recombinant Human Nanos homolog 2 (NANOS2) from BIOMATIK |
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| Product Specific References | n/a |
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