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| Product Name | Sema Domain, Seven thrombospondin Repeats (Type 1 and Type 1-Like), Transmembrane Domain (TM) and Short Cytoplasmic Domain, (Semaphorin) 5A (SEMA5A) (AA 23-765) protein (His tag) |
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| Description | Semaphorin-5A (SEMA5A) is a member of the Semaphorin family of axon guidance molecules. SEMA5A is a 140 kDa protein. Class 5 Semaphorins are type I transmembrane glycoproteins with an N- terminal Sema domain and multiple juxtamembrane type 1 Thrombospondin (TSP) repeats within their extracellular domains. SEMA5A is expressed in neuroepithelial cells surrounding retinal axons, oligodendrocytes, the base of limb buds, the mesoderm surrounding cranial vessels , and the cardiac atrial septum and endocardial cushions, Human SEMA5A cDNA encodes a signal sequence, a extracellular domain (ECD), a transmembrane sequence and an cytoplasmic portion. SEMA5A mutations have been implicated in the genetic syndrome,cri-du-chat,while some polymorphisms may increase risk for neurodegenerative diseases such as Parkinson. The expression of SEMA5A may be upregulated in metastatic cancer cells and downregulated in autism.Alternative Names: Semaphorin-5A, Semaphorin-F, Sema F, SEMA5A, SEMAF |
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| Size | 1 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | wu:fa95e03|wu:fi41a04|SEMAF|semF|5930434A13|9130201M22Rik|AI464145|Semaf |
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| Gene, Accession, CAS # | Gene ID: 9037 |
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| Catalog # | ABIN1097497 |
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| Order / More Info | Sema Domain, Seven thrombospondin Repeats (Type 1 and Type 1-Like), Transmembrane Domain (TM) and Short Cytoplasmic Domain, (Semaphorin) 5A (SEMA5A) (AA 23-765) protein (His tag) from ANTIBODIES-ONLINE GmbH |
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| Product Specific References | n/a |
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