产品名称 BHLHE40 Antibody from CREATIVE DIAGNOSTICS
产品货号 CABT-B1918
产品价格 现货询价,电话:010-67529703
产品规格 n/a
产品品牌 CREATIVE DIAGNOSTICS
产品概述
产品详情
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Antigenic SpecificityBHLHE40
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formatunconjugated
Sizen/a
Concentrationn/a
ApplicationsWB
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DescriptionRabbit Anti-Human BHLHE40 polyclonal antibody for WB. Class E basic helix-loop-helix protein 40 (UniProt O14503; also known as Basic helix-loop-helix domain containing class B2, Class B basic helix-loop-helix protein 2, Differentially expressed in chondrocytes 1, Differentially expressed in chondrocytes protein 1, Differentiated embryo chondrocyte expressed gene 1, Enhancer-of-split and hairy-related protein 2, SHARP-2, Stimulated by retinoic acid gene 13 protein) is encoded by the BHLHE40 (also known as BHLHB2, DEC1, HLHB2, SHARP2, STRA13) gene (Gene ID 8553) in human. DEC1 (differentially expressed in chondrocytes 1) and DEC2 are E-box-binding transcription factors that exhibit a circadian expression pattern. Both proteins act to repress the Clock/Bmal1-activated E-box promoters via direct E-box binding rather than Bmal1 interaction. In addition, DEC1 is shown to negatively regulate the expression of DEC2. Markedly increased DEC1 expression is observed in colon carcinomas, whereas the opposite trend is seen with DEC2. Likewise cellular DEC1 over-expression results in a proportional decrease in DEC2 level.
ImmunogenKLH-conjugated linear peptide corresponding to human BHLHE40/DEC1.
Other Namesn/a
Gene, Accession #Gene ID: 8553, UniProt: O14503
Catalog #CABT-B1918
Price
Order / More InfoBHLHE40 Antibody from CREATIVE DIAGNOSTICS
Product Specific Referencesn/a
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