| 产品详情 |
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| Antigenic Specificity | CD14 Molecule (CD14) |
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| Clone | B-A8 |
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| Host Species | Mouse |
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| Reactive Species | human |
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| Isotype | IgG1 |
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| Format | Protein A purified |
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| Size | 0.1 mg |
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| Concentration | n/a |
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| Applications | Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)),ELISA,Flow Cytometry (FACS) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | CD14 is a 55 kDa GPI-anchored glycoprotein, constitutively expressed on the surface of mature monocytes, macrophages, and neutrophils, where serves as a multifunctional lipopolysaccharide receptor, it is also released to the serum both as a secreted and enzymatically cleaved GPI-anchored form. CD14 binds lipopolysaccharide molecule in a reaction catalyzed by lipopolysaccharide-binding protein (LBP), an acute phase serum protein. The soluble sCD14 is able to discriminate slight structural differences between lipopolysaccharides and is important for neutralization of serum allochthonous lipopolysaccharides by reconstituted lipoprotein particles. CD14 affects allergic, inflammatory and infectious processes. |
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| Immunogen | Human monocytes |
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| Other Names | n/a |
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| Gene, Accession # | Gene ID: 929 |
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| Catalog # | ABIN93977 |
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| Price | |
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| Order / More Info | CD14 Molecule (CD14) Antibody from ANTIBODIES-ONLINE GmbH |
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| Product Specific References | PubMed: 12679473, 7542233, 18025213, 17986374, 15954901, 10614771, 17545278, 2448876 |
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