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Product Name | Multiple Coagulation Factor Deficiency 2 (MCFD2) (AA 27-146) protein (T7 tag) |
Description | The MCFD2-LMAN1 complex forms an explicit cargo receptor for the ER-to-Golgi transport of selected proteins. MCFD2 is involved in the secretion of coagulation factors. MCFD2 is expressed by neural stem/progenitor cells of the hippocampus, and localized to region where neurogenesis persists throughout life. MCFD2 prevents NSC cell death and maintains stem cell characteristics. MCFD2 forms a complex with LAMN1 that facilitates the transport of coagulation factors V and VIII from the endoplasmic reticulum to the Golgi apparatus through an endoplasmic reticulum Golgi intermediate compartment. Mutations in the MCFD2 cause Factor V and Factor VIII combined deficiency Synonyms: SDNSF, LMAN1IP, Multiple coagulation factor deficiency protein 2, Neural stem cell-derived neuronal survival protein, MCFD2, F5F8D, DKFZp686G21263 |
Size | 1 mg |
Concentration | n/a |
Applications | n/a |
Other Names | hm:zeh1186|wu:fc23b10|wu:fd50d08|zgc:103713|zgc:109915|MCFD2|DKFZp469B098|F5F8D|F5F8D2|LMAN1IP|SDNSF|1810021C21Rik|F5f8d|Lman1ip|Sdnsf |
Gene, Accession, CAS # | Gene ID: 90411 |
Catalog # | ABIN807669 |
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Order / More Info | Multiple Coagulation Factor Deficiency 2 (MCFD2) (AA 27-146) protein (T7 tag) from ANTIBODIES-ONLINE GmbH |
Product Specific References | n/a |
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