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Product Name | Sirtuin 2 (SIRT2) (AA 2-389) (Active) protein (His tag) |
Description | Sirtuin 2 (SIRT2) is a NAD-dependent protein deacetylase, which deacetylates the 'Lys-40' of alpha-tubulin. It is involved in the control of mitotic exit in the cell cycle. Furthermore, a variety of age-associated diseases such as type 2 diabetes, obesity, osteoporosis, and Alzheimer's disease are associated with sirtuins. Selective inhibition of Sirtuin 2 achieves neuroprotection and identifies Sirtuin 2 to be a potential therapeutic avenue in Huntington's and Parkinson's disease. |
Size | 50 µg |
Concentration | n/a |
Applications | SDS-PAGE (SDS) |
Other Names | CG5085|D.mel2|Dmel\\CG5085|SIRT2|dSIRT2|sir2|Sirt2|BmSirt2|AtSRT2|SIRTUIN 2|T2K12.8|sirtuin 2|SIR2|SIR2L|SIR2L2|5730427M03Rik|Sir2l|wu:fb57d05|zgc:55966|zgc:77003 |
Gene, Accession, CAS # | Gene ID: 22933 |
Catalog # | ABIN1344340 |
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Order / More Info | Sirtuin 2 (SIRT2) (AA 2-389) (Active) protein (His tag) from ANTIBODIES-ONLINE GmbH |
Product Specific References | n/a |
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