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| Antigenic Specificity | B-Cell CLL/lymphoma 10 (BCL10) |
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| Clone | 4F8 |
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| Host Species | Mouse |
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| Reactive Species | human, mouse |
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| Isotype | IgG1 |
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| Format | purified |
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| Size | 100 µL |
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| Concentration | n/a |
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| Applications | ELISA,Flow Cytometry (FACS),Immunocytochemistry (ICC),Immunohistochemistry (IHC),Western Blotting (WB) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Bcl-10 (B-cell CLL/lymphoma 10), also known as CLAP, Me10, CIPER, c-E10, CARMEN. Entrez Protein NP_003912. It is a protein containing a caspase recruitment domain (CARD). It plays an important role in apoptosis and activating NF-kappaB. The research suggested that it interacted with other CARD domain containing proteins including CARD9, 10, 11 and 14, which were thought to function as upstream regulators in NF-kappaB signaling. Bcl-10 is found to form a complex with MALT1 which encoded by another gene known to be translocated in MALT lymphoma. MALT1 and Bcl-10 are thought to synergize in the activation of NF-kappaB, and the deregulation of either of them may contribute to the same pathogenetic process that leads to the malignancy. |
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| Immunogen | Purified recombinant fragment of human BCL-10 expressed in E. Coli. |
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| Other Names | BCL10|AI132454|BCL-10|C81403|CARMEN|CIPER|CLAP|ME10|cE10|c-E10|mE10 |
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| Gene, Accession # | Gene ID: 8915,12042 |
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| Catalog # | ABIN1724629 |
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| Price | |
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| Order / More Info | B-Cell CLL/lymphoma 10 (BCL10) Antibody from ANTIBODIES-ONLINE GmbH |
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| Product Specific References | PubMed: 9989495, 11262391, 11259443 |
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