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| Product Name | Recombinant Mouse Legumain (Lgmn) |
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| Description | Purity > 90% as determined by SDS-PAGE. MW: 36.8kDa. Full Length of Mature Protein: 18-325aa. N-terminal 6xHis-tagged. Mus musculus (Mouse). Has a strict specificity for hydrolysis of asparaginyl bonds. Can also cleave aspartyl bonds slowly, especially under acidic conditions. May be involved in the processing of proteins for MHC class II antigen presentation in the lysosomal/endosomal system. Required for normal lysosomal protein degradation in renal proximal tubules. Required for normal degradation of internalized EGFR. Plays a role in the regulation of cell proliferation via its role in EGFR degradation. |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | RUO |
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| Other Names | Asparaginyl endopeptidase; Protease, cysteine 1 |
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| Gene, Accession, CAS # | Lgmn, UniProt: O89017 |
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| Catalog # | RPC24788 |
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| Price | |
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| Order / More Info | Recombinant Mouse Legumain (Lgmn) from BIOMATIK |
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| Product Specific References | n/a |
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