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Product Name | Recombinant Human Mesencephalic astrocyte-derived neurotrophic factor protein (MANF) (Active) |
Description | Purity > 95% as determined by SDS-PAGE and HPLC. MW: 18.2kDa. Full Length of Mature Protein: 25-182aa. tag-Free. Homo sapiens (Human). Selectively promotes the survival of dopaminergic neurons of the ventral mid-brain. Modulates GABAergic transmission to the dopaminergic neurons of the substantia nigra. Enhances spontaneous, as well as evoked, GABAergic inhibitory postsynaptic currents in dopaminergic neurons (By similarity). Inhibits cell proliferation and endoplasmic reticulum (ER) stress-induced cell death. {ECO:0000250, ECO:0000269|PubMed:12794311, ECO:0000269|PubMed:18561914}. |
Size | 100ug |
Concentration | n/a |
Applications | RUO |
Other Names | Arginine-rich protein, |
Gene, Accession, CAS # | MANF,ARMET,ARP, UniProt: P55145 |
Catalog # | RPC26779 |
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Order / More Info | Recombinant Human Mesencephalic astrocyte-derived neurotrophic factor protein (MANF) (Active) from BIOMATIK |
Product Specific References | n/a |
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