产品详情 |
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Product Name | Ac-DEVD-CHO |
Description | Purity >98%. Ac-DEVD-CHO is a potent inhibitor of the Group II caspases, caspase-3 and caspase-7 (Ki s = 0.23 and 1.6 nM, respectively). Notably, it also inhibits other caspases (Ki s = 18, 1710, 132, 205, 31, 0.92, 60, and 12 nM for caspases-1, -2, -4, -5, -6, -8, -9, and -10, respectively). Caspase inhibitors in the aldehyde form, like this compound, are typically reversible, whereas methyl ketone forms, like Ac-DEVD-CMK , are irreversible. Caspase inhibitors interfere with the initiation of apoptosis and have numerous possible clinical applications. |
Size | n/a |
Concentration | n/a |
Applications | n/a |
Other Names | N-acetyl-L-a-aspartyl-L-a-glutamyl-N-(2-carboxyl-1-formylethyl)-L-valinamide, N-Ac-Asp-Glu-Val-Asp-CHO |
Gene, Accession, CAS # | CAS: 184179-08-6 |
Catalog # | LS-H5413 |
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Order / More Info | Ac-DEVD-CHO from LIFESPAN BIOSCIENCES INC. |
Product Specific References | n/a |
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