产品详情 |
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Product Name | Ac-DEVD-AFC |
Description | Purity >98%. During apoptosis, activated caspase-3 cleaves several substrates, including poly(ADP-ribose) polymerase, which it specifically targets at the amino sequence DEVD. Ac-DEVD-AFC is a fluorogenic substrate for activated caspase-3 (Km = 9.7 µM), as well as related caspases. Caspase activity can be quantified by fluorescent detection of free AFC (also known as 7-amino-4-trifluoromethylcoumarin), which is excited at 400 nm and emits at 505 nm. |
Size | n/a |
Concentration | n/a |
Applications | n/a |
Other Names | N-acetyl-L-a-aspartyl-L-a-glutamyl-L-valyl-N-[2-oxo-4-(trifluoromethyl)-2H-1-benzopyran-7-yl]-L-a-asparagine, Caspase-3 Substrate (Fluorogenic), N-Acetyl-Asp-Glu-Val-Asp-7-amino-4-Trifluoromethylcoumarin |
Gene, Accession, CAS # | CAS: 201608-14-2 |
Catalog # | LS-H5421 |
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Order / More Info | Ac-DEVD-AFC from LIFESPAN BIOSCIENCES INC. |
Product Specific References | n/a |
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