产品详情 |
Edit |   |
Antigenic Specificity | PTH / Parathyroid Hormone |
Clone | PTH/2295R |
Host Species | Recombinant Rabbit |
Reactive Species | human |
Isotype | IgG |
Format | Protein A/G purified |
Size | n/a |
Concentration | n/a |
Applications | IHC-Fx, SDS-PAGE |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | PTH / Parathyroid Hormone Antibody (clone PTH/2295R) LS-C751327. Specificity: Epitope of this MAb maps in between aa 1-34. PTH is a hormone produced by the parathyroid gland that regulates the concentration of calcium and phosphorus in extracellular fluid. This hormone elevates blood Ca2+ levels by dissolving the salts in bone and preventing their renal excretion. It is produced in the parathyroid gland as an 84 amino acid single chain polypeptide. It can also be secreted as N-terminal truncated fragments or C-terminal fragments after intracellular degradation, as in case of hypercalcemia. Defects in this gene are a cause of familial isolated hypoparathyroidism (FIH) - also called autosomal dominant hypoparathyroidism or autosomal dominant hypocalcemia. FIH is characterized by hypocalcemia and hyperphosphatemia due to inadequate secretion of parathyroid hormone. Symptoms are seizures, tetany and cramps. FIH exist both as autosomal dominant and recessive forms of hypoparathyroidism. |
Immunogen | Synthetic peptide corresponding to amino acids 1 to 34 of mature PTH conjugated to a carrier. Antigen Molecular Weight: 9 kDa |
Other Names | PTH, Parathyroid hormone, Parathyroid hormone 1, Parathyrin, Parathormone, PTH1 |
Gene, Accession # | PTH, Gene ID: 5741 |
Catalog # | LS-C751327 |
Price | |
Order / More Info | PTH / Parathyroid Hormone Antibody from LIFESPAN BIOSCIENCES INC. |
Product Specific References | n/a |
产品资料 |
|
|