产品详情 |
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Antigenic Specificity | ITGB3 / Integrin Beta 3 / CD61 |
Clone | monoclonal |
Host Species | Hamster |
Reactive Species | mouse, rat |
Isotype | IgG |
Format | phycoerythrin (RPE) conjugate |
Size | n/a |
Concentration | n/a |
Applications | Flo (1:1 - 1:10), IP |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | ITGB3 / Integrin Beta 3 / CD61 Antibody (RPE) LS-C44646. Recognizes the murine integrin beta 3 subunit (CD61), a 90kD type I membrane protein, which is expressed primarily on megakaryocytes, platelets, monocytes, macrophages, granulocytes and endothelial cells. CD61 associates with either the alpha IIb integrin (CD41) or the alpha V integrin (CD51) to form the platelet glycoprotein complex IIb/IIIa and the vitronectin receptor (VNR) respectively. The heterodimers formed with CD61 are receptors for a variety of ligands including fibrinogen, fibronectin, von Willebrand's factor (vWF), vitronectin and thrombospondin. Clone HM beta 3.1 is reported to partially inhibit the binding of CD61 to fibronectin. XXX recommend the use of MCA2299EL for this purpose. |
Immunogen | Mouse alpha 5 beta 3 protein purified from the mouse hybridoma 2B4. |
Other Names | ITGB3, BDPLT2, CD61 antigen, GT, gp3A, CD61, GPIIIa, Integrin beta-3 |
Gene, Accession # | ITGB3, Gene ID: 3690 |
Catalog # | LS-C44646 |
Price | |
Order / More Info | ITGB3 / Integrin Beta 3 / CD61 Antibody from LIFESPAN BIOSCIENCES INC. |
Product Specific References | n/a |
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