产品详情 |
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Antigenic Specificity | ITGB3 / Integrin Beta 3 / CD61 |
Clone | HM beta 3.1 |
Host Species | Hamster |
Reactive Species | mouse, rat |
Isotype | IgG |
Format | Protein G purified |
Size | n/a |
Concentration | n/a |
Applications | Flo (1:10 - 1:25), IP |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | ITGB3 / Integrin Beta 3 / CD61 Antibody (clone HM beta 3.1) LS-C44640. Recognizes the murine integrin beta 3 subunit (CD61), a 90kD a type I membrane protein, which is expressed primarily on megakaryocytes, platelets, monocytes, macrophages, granulocytes and endothelial cells. CD61 associates with either the alpha IIb integrin (CD41) or the alpha V integrin (CD51) to form the platelet glycoprotein complex IIb/IIIa and the vitronectin receptor (VNR) respectively. The heterodimers formed with CD61 are receptor for a variety of ligands including fibrinogen, fibronectin, von Willebrand's factor (vWF), vitronectin and thrombospondin. Clone HM beta 3-1 is reported to partially inhibit the binding of CD61 to fibronectin. |
Immunogen | Mouse alpha 5 beta 3 protein purified from the mouse hybridoma 2B4. |
Other Names | ITGB3, BDPLT2, CD61 antigen, GT, gp3A, CD61, GPIIIa, Integrin beta-3 |
Gene, Accession # | ITGB3, Gene ID: 3690 |
Catalog # | LS-C44640 |
Price | |
Order / More Info | ITGB3 / Integrin Beta 3 / CD61 Antibody from LIFESPAN BIOSCIENCES INC. |
Product Specific References | n/a |
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