| 产品详情 |
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| Antigenic Specificity | pi-3 Kinase P85 beta |
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| Clone | 8D9-D5-F8 |
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| Host Species | Mouse |
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| Reactive Species | human |
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| Isotype | IgG1 |
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| Format | unconjugated |
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| Size | 100 µL |
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| Concentration | n/a |
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| Applications | Western Blotting (WB) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Phosphatidylinositol 3-kinase (PI3K) is a lipid kinase that phosphorylates phosphatidylinositol and similar compounds, creating second messengers important in growth signaling pathways. PI3K functions as a heterodimer of a regulatory and a catalytic subunit. The protein encoded by this gene is a regulatory component of PI3K. Two transcript variants, one protein coding and the other non-protein coding, have been found for this gene. Binds to activated (phosphorylated) protein-tyrosine kinases, through its SH2 domain, and acts as an adapter, mediating the association of the p110 catalytic unit to the plasma membrane. Subunit structure: Heterodimer of a regulatory subunit PIK3R2 and a p110 catalytic subunit (PIK3CA, PIK3CB or PIK3CD). Interacts with AXL. Interacts with FLT1 (tyrosine-phosphorylated) and FLT4 (tyrosine-phosphorylated). Interacts with NYAP1, NYAP2 and MYO16. Subcellular location: Cytosol. Sequence similarities: Belongs to the PI3K p85 subunit family. Contains 1 Rho-GAP domain. Contains 2 SH2 domains. Contains 1 SH3 domain. |
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| Immunogen | Purified recombinant human PI3 Kinase p85 beta protein fragments expressed in E.coli. |
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| Other Names | p85beta|MPPH|P85B|p85|p85-BETA |
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| Gene, Accession # | Gene ID: 5296 |
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| Catalog # | ABIN2169560 |
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| Order / More Info | pi-3 Kinase P85 beta Antibody from ANTIBODIES-ONLINE GmbH |
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| Product Specific References | n/a |
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