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| Product Name | Recombinant Mouse Interleukin-23 subunit alpha (Il23a), partial |
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| Description | Purity > 90% as determined by SDS-PAGE. MW: 23.7kDa. Partial: 22-196. N-terminal 6xHis-tagged. Mus musculus (Mouse). Associates with IL12B to form the IL-23 interleukin, a heterodimeric cytokine which functions in innate and adaptive immunity. IL-23 may constitute with IL-17 an acute response to infection in peripheral tissues. IL-23 binds to a heterodimeric receptor complex composed of IL12RB1 and IL23R, activates the Jak-Stat signaling cascade, stimulates memory rather than naive T-cells and promotes production of proinflammatory cytokines. IL-23 induces autoimmune inflammation and thus may be responsible for autoimmune inflammatory diseases and may be important for tumorigenesis. |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | RUO |
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| Other Names | IL-23 subunit alpha; IL-23-A; Alternative name (s); Interleukin-23 subunit p19; IL-23p19 |
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| Gene, Accession, CAS # | Il23a, UniProt: Q9EQ14 |
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| Catalog # | RPC23555 |
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| Order / More Info | Recombinant Mouse Interleukin-23 subunit alpha (Il23a), partial from BIOMATIK |
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| Product Specific References | n/a |
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