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| Antigenic Specificity | AMYLOID PRECURSOR PROTEIN |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse, rat |
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| Isotype | n/a |
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| Format | n/a |
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| Size | 0.1 mg |
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| Concentration | IgG concentration 0.5 mg/ml |
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| Applications | Immunohistology Paraffin*, Western Blot (WB) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | RABBIT ANTI AMYLOID PRECURSOR PROTEIN (C-TERMINAL). This item recognises both intact APP, and also the C99 fragment generated by Beta-secretase.The sequence recognised by this antibody corresponds to amino acids 85-99 of the C99 fragment. The C99 fragment itself is a substrate for gamma-secretase to generate the 4kD beta amyloid peptide which is found in the brains of Alzheimer's disease patients. APP also inhibits Notch signaling through it's interaction with NUMB. |
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| Immunogen | Synthetic peptide corresponding to amino acids 737-751 of human APP |
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| Other Names | amyloid beta A4 protein isoform a; Amyloid beta A4 protein; amyloid beta A4 protein; alzheimer disease amyloid protein; beta-amyloid peptide; beta-amyloid peptide(1-40); beta-amyloid peptide(1-42); cerebral vascular amyloid peptide; peptidase nexin-II; preA4; protease nexin-II; amyloid beta (A4) precursor protein; ABPP; APPI; APP; Alzheimer disease amyloid protein; Cerebral vascular amyloid peptide; CVAP; PreA4; Protease nexin-II; PN-II, APP; APP; AAA; AD1; PN2; ABPP; APPI; CVAP; ABETA; PN-II; C |
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| Gene, Accession # | Gene ID: 351, NCBI: NP_000475.1, UniProt: P05067 |
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| Catalog # | MBS221602 |
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| Price | |
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| Order / More Info | AMYLOID PRECURSOR PROTEIN Antibody from MYBIOSOURCE INC. |
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| Product Specific References | n/a |
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