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| Product Name | MMP-3 Activity Fluorometric Assay Kit |
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| Description | The matrix metalloproteinase-3 (MMP-3, stromelysin-1) exhibits a number of activities that would make it a particularly good tumor promoter. Like several other MMPs, MMP-3 was first cloned and later recloned as a cancer-specific gene. In addition to degrading numerous extracellular matrix components, MMP-3 can activate gelatinase B, the collagenases and several serpin-type serine proteinase inhibitors. Moreover, it can release a number of cell surface molecules, including E-cadherin, a known contributor to cancer development. In MMP-3 Assay Kit, MMP-3 hydrolyzes a specific FRET substrate to release the quenched fluorescent group Mca, which can be detected fluorometrically at Ex/Em = 325/393 nm. The kit provides a rapid, simple, sensitive and reliable test which can also be used as a high throughput assay of MMP-3 activity. The assay sensitivity is < 50 µU. This kit can be used with our MMP-3 inhibitor, GM6001 as a control. In addition, we also offer a human recombinant MMP-3 enzyme and a MMP-3 inhibitor Screening Kit, separately. |
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| Size | 100 assays |
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| Concentration | n/a |
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| Applications | The assay sensitivity is < 50 µU. |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | Kit-2213 |
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| Price | |
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| Order / More Info | MMP-3 Activity Fluorometric Assay Kit from CREATIVE BIOMART |
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| Product Specific References | n/a |
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