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| Product Name | Recombinant Human 7, 8-dihydro-8-oxoguanine triphosphatase (NUDT1) |
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| Description | 19-197aa. MW: 22.3 kDa. Purity >85% as determined by SDS-PAGE. Antimutagenic. Acts as a sanitizing enzyme for oxidized nucleotide pools, thus suppressing cell dysfunction and death induced by oxidative stress. Hydrolyzes 8-oxo-dGTP, 8-oxo-dATP and 2-OH-dATP, thus preventing misincorporation of oxidized purine nucleoside triphosphates into DNA and subsequently preventing A:T to C:G and G:C to T:A transversions. Able to hydrolyze also the corresponding ribonucleotides, 2-OH-ATP, 8-oxo-GTP and 8-ox |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | [2-hydroxy-dATP diphosphatase (EC:3.6.1.56); 8-oxo-dGTPase; Nucleoside diphosphate-linked moiety X motif 1; MTH1] |
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| Gene, Accession, CAS # | NUDT1, Gene ID: 4521, Accession: NP_002443.3 |
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| Catalog # | MBS7111004 |
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| Order / More Info | Recombinant Human 7, 8-dihydro-8-oxoguanine triphosphatase (NUDT1) from MYBIOSOURCE INC. |
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| Product Specific References | Genomic structure and chromosome location of the human mutT homologue gene MTH1 encoding 8-oxo-dGTPase for prevention of A:T to C:G transversion. Furuichi M., Yoshida M.C., Oda H., Tajiri T., Nakabeppu Y., Tsuzuki T., Sekiguchi M.Genomics 24:485-490 (1994) |
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