产品详情 |
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Antigenic Specificity | CCR5, aa3-30 |
Clone | polyclonal |
Host Species | Goat |
Reactive Species | human |
Isotype | n/a |
Format | affinity purified |
Size | n/a |
Concentration | n/a |
Applications | ELISA (1:50000), IHC, IHC-Fr, IHC-P (1:300), WB (1:1000) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | CCR5 Antibody (aa3-30) LS-C187838. Recognizes human CD195, also known as C-C chemokine receptor type 5, CCR5 or C-C CKR-5. CD195 is a 353 amino acid ~37 kD multiple pass transmembrane glycoprotein and member of the G-protein coupled receptor 1 family, preferentially expressed by a subset of memory Th1 (type 1 helper T) cells. Binds to an epitope within the N-terminal (NT) region of CD195. CD195 acts as a high-affinity receptor for several chemotactic chemokines, including MIP-1 alpha (macrophage inflammatory protein 1 alpha), MIP-1 beta, and RANTES (regulated on activation normal T expressed and secreted protein). CD195 is also a major co-receptor for HIV-1 infection, with variations in the CD195 gene, influencing the rate of progression into AIDS. Is suitable for use in immunocytochemistry on human peripheral blood leucocytes. |
Immunogen | Synthetic peptide YQVSSPIYDINYYTSEPCQKINVKQIAA corresponding to amino acids 3-30 within the N-terminal region of human CD195. Percent identity by BLAST analysis: Human (100%); Chimpanzee, Monkey (96%); Orangutan, Baboon (93%). |
Other Names | CCR5, C-C chemokine receptor 5, CD195 antigen, CD195, C-C CKR-5, Chemokine c-c motif receptor 5, Chemr13, CMKBR5, CKR5, Cc chemokine receptor 5, CCCKR5, CCR-5, Ccr5 receptor, Chemokine receptor CCR5, HIV-1 fusion coreceptor, IDDM22, C-C chemokine receptor type 5, CC-CKR-5, CKR-5 |
Gene, Accession # | CCR5, Gene ID: 1234 |
Catalog # | LS-C187838 |
Price | |
Order / More Info | CCR5, aa3-30 Antibody from LIFESPAN BIOSCIENCES INC. |
Product Specific References | n/a |
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