| 产品详情 |
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| Antigenic Specificity | LAMP2 / CD107b |
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| Clone | AC17 |
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| Host Species | Mouse |
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| Reactive Species | dog, mink, human |
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| Isotype | IgG1 |
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| Format | Protein G purified |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | Flo, IF, IP, WB (1:100 - 1:500) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | LAMP2 / CD107b Antibody (clone AC17) LS-C188336. Recognizes canine CD107b, otherwise known as LAMP-2, a 95kD heavily-glycosylated type I integral lysosomal glycoprotein, shown to share high N-terminal amino acid sequence homology with human, mouse and rat CD107b. Lysosomes are membrane-bound organelles found within the cytoplasm of most cells, which contain hydrolytic enzymes and act as the major compartment for heterophagic and autophagic digestion. Members of the lysosomal-associated membrane protein family (LAMPS) are believed to play an important role in protecting the lysosomal membrane from protease degradation and are involved in lectin-mediated cell adhesion. Evidence shows that CD107b is involved in the lysosomal uptake of cytosolic proteins and the endocytic pathway and human studies have revealed a correlation between the level of surface expression of CD107b on tumor cells and their metastatic potential. Clone AC17 has been shown as suitable for use in Electron Microscopy. Does not react with: Mouse, Rat |
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| Immunogen | MDCK (Madin-Darby Canine Kidney) cells. |
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| Other Names | LAMP2, CD107b, CD107b antigen, LAMPB, LGP110, LAMP-2 |
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| Gene, Accession # | LAMP2, Gene ID: 3920 |
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| Catalog # | LS-C188336 |
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| Price | |
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| Order / More Info | LAMP2 / CD107b Antibody from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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