| 产品详情 |
| Edit |   |
|---|
| Product Name | Foscarnet (sodium salt) |
|---|
| Description | An inhibitor of viral DNA and RNA polymerases and reverse transcriptase; inhibits DNA polymerase from HSV-1, HSV-2, CMV, and Epstein-Barr virus (IC50s = 0.3-22 µM); inhibits DNA polymerase α, but not β or γ, from HeLa cells (IC50 = 32 µM); inhibits RNA polymerase from influenza A and B (IC50s = 29 and 61 µM, respectively) and reverse transcriptase from avian myeloblastosis virus and murine leukemia virus (IC50s = 0.7-55 µM); inhibits replication of HSV-2 in Vero cells (IC100 = 1,000 µM) and laboratory and clinical isolates of CMV in MRC-5 cells (IC50s = 102.6-163.8 µM); reduces mortality in mouse models of infection with murine CMV or HSV-2 when administered alone (ED50s = 242 and 170 mg/kg, respectively) or in combination with ganciclovir (ED50s = 57 and <32 mg/kg, respectively) |
|---|
| Size | 1 g |
|---|
| Concentration | n/a |
|---|
| Applications | n/a |
|---|
| Other Names | Trisodium Phosphonoformate |
|---|
| Gene, Accession, CAS # | CAS: 63585-09-1 |
|---|
| Catalog # | 20774-1 |
|---|
| Price | |
|---|
| Order / More Info | Foscarnet (sodium salt) from CAYMAN CHEMICAL COMPANY |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|