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| Product Name | N-(n-Butyl)deoxygalactonojirimycin |
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| Description | Purity >95%. N-(n-Butyl)deoxygalactonojirimycin is an inhibitor of Alpha-D-galactosidase. It has also been shown to prevent glucosylceramide biosynthesis both in vitro and in mouse models of lysosome storage disorders by inhibiting the ceramide-specific glucosyltransferase, UDP-glucose ceramide glucosyltransferase (IC50 = 41.4 µM) without affecting Alpha-glucosidase I and II or Beta-glucocerebrosidase (IC50 s > 1 mM). This compound has been used to sensitize cultured chronic lymphocytic leukemia cells to the chemotherapeutic agents cladribine , chlorambucil , and fludarabine . |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 1-butyl-2R-(hydroxymethyl)-3S,4R,5S-piperidinetriol, Lucerastat, NBDGJ |
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| Gene, Accession, CAS # | CAS: 141206-42-0 |
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| Catalog # | LS-H8859 |
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| Order / More Info | N-(n-Butyl)deoxygalactonojirimycin from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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| 产品资料 |
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