产品详情 |
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Antigenic Specificity | BTLA / CD272 |
Clone | MIH26 |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG2b |
Format | affinity purified |
Size | n/a |
Concentration | n/a |
Applications | Flo (1:10 - 1:200), IHC, IHC-Fr |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | BTLA / CD272 Antibody (clone MIH26) LS-C58210. Detects human CD272, also known as B- and T-lymphocyte attenuator (BTLA). CD272 is a type I transmembrane glycoprotein which is structurally and functionally related to cytotoxic T lymphocyte antigen-4 (CTLA-4), and programmed death-1 (PD-1). CD272 is a T-cell inhibitory receptor that regulates T cell activation through its interaction with herpes virus entry mediator (HVEM), a co-stimulator receptor of the TNFR family. CD272 may negatively regulate T-cell dependent autoimmune reaction, and polymorphisms in its gene have been associated with Rheumatoid Arthritis. |
Immunogen | BTLA - transfected L cells. |
Other Names | BTLA, BTLA1, B and T lymphocyte associated, CD272, B and T lymphocyte attenuator, B- and T-lymphocyte attenuator, CD272 antigen |
Gene, Accession # | BTLA, Gene ID: 151888 |
Catalog # | LS-C58210 |
Price | |
Order / More Info | BTLA / CD272 Antibody from LIFESPAN BIOSCIENCES INC. |
Product Specific References | n/a |
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