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| Product Name | Tumor Necrosis Factor Receptor Superfamily, Member 21 (TNFRSF21) (AA 42-350) protein (Fc Tag) |
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| Description | Tumor Necrosis Factor Receptor Superfamily Member 21 (TNFRSF21) is a type I transmembrane receptor that includes four extracellular cysteine-rich motifs and a cytoplasmic death domain. DR6 is highly expressed in heart, brain, placenta, pancreas, lymph node, thymus and prostate. DR6 may activate NF-kappa-B and JNK to promote apoptosis and T-cell differentiation. In addition, DR6 binds with N-APP, which is released by the deprivation of Trophic-factor. It triggers caspase activation and degeneration of both neuronal cell bodies (via caspase-3) and axons (via caspase-6). DR6 is also expressed on the tumor cell lines and can be induced by TNF-alpha.Alternative Names: Tumor Necrosis Factor Receptor Superfamily Member 21, Death Receptor 6, CD358, TNFRSF21, DR6, UNQ437/PRO868 |
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| Size | 500 µg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | TNFRSF21|tnfrsf21|MGC146356|BM-018|CD358|DR6|AA959878|R74815|TR7|dr6|im:6795346|wu:fa55e01|wu:fb02e11|wu:fc29a09|wu:fi27h08 |
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| Gene, Accession, CAS # | Gene ID: 27242 |
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| Catalog # | ABIN1692268 |
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| Order / More Info | Tumor Necrosis Factor Receptor Superfamily, Member 21 (TNFRSF21) (AA 42-350) protein (Fc Tag) from ANTIBODIES-ONLINE GmbH |
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| Product Specific References | n/a |
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