产品详情 |
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Antigenic Specificity | TLR3, C-Terminus |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | mouse, human |
Isotype | n/a |
Format | purified |
Size | n/a |
Concentration | n/a |
Applications | WB (1 - 2 µg/ml) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | TLR3 Antibody (C-Terminus) LS-C42338. Recognizes human CD283, otherwise known as toll receptor 3, a 103.8 kD member of the evolutionarily conserved toll-like receptor family (TLRs), expressed at high levels in the placenta and pancreas and also expressed by dendritic cells. TLRs play an important role in the recognition of invading microbial pathogens during innate immunity, acting through adaptor molecules such as MyD88 and TRAF6. CD283 acts via a cytokine signaling pathway to induce the activation of NF-kappaB and type I interferons, and has been shown to recognize double-stranded viral RNA, including that of the Influenza A and West Nile virus. Has been shown as suitable for use in IHC on EL4 cytospins at 1 ug/ml. |
Immunogen | Synthetic peptide corresponding to a 15 amino acid sequence located near human CD283 carboxy-terminus. |
Other Names | TLR3, CD283, Toll-like receptor 3, CD283 antigen, IIAE2 |
Gene, Accession # | TLR3, Gene ID: 7098 |
Catalog # | LS-C42338 |
Price | |
Order / More Info | TLR3, C-Terminus Antibody from LIFESPAN BIOSCIENCES INC. |
Product Specific References | n/a |
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