| 产品详情 |
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| Antigenic Specificity | MYD88 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human |
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| Isotype | n/a |
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| Format | Protein G purified |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | ELISA, IF |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | MYD88 Antibody LS-C501677. Specificity: Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. Acts via IRAK1, IRAK2, IRF7 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Increases IL-8 transcription. Involved in IL-18-mediated signaling pathway. Activates IRF1 resulting in its rapid migration into the nucleus to mediate an efficient induction of IFN-beta, NOS2/INOS, and IL12A genes. MyD88-mediated signaling in intestinal epithelial cells is crucial for maintenance of gut homeostasis and controls the expression of the antimicrobial lectin REG3G in the small intestine. |
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| Immunogen | Recombinant Human Myeloid differentiation primary response protein MyD88 protein (1-282AA) |
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| Other Names | MYD88, MYD88D |
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| Gene, Accession # | MYD88, Gene ID: 4615 |
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| Catalog # | LS-C501677 |
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| Price | |
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| Order / More Info | MYD88 Antibody from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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