产品详情 |
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Antigenic Specificity | TLR9, aa205-235 |
Clone | polyclonal |
Host Species | Goat |
Reactive Species | human |
Isotype | n/a |
Format | affinity purified |
Size | n/a |
Concentration | n/a |
Applications | IHC, IHC-P (1:250), WB (1:1000) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | TLR9 Antibody (aa205-235) LS-C187854. Recognizes an epitope within the N-terminal (NT) region of CD289, otherwise known as Toll-like receptor 9 (TLR9), a type I transmembrane glycoprotein and member of the toll-like receptor family, which triggers MyD88 and TRAF6, resulting in NF-kappaB activation, cytokine secretion and the inflammatory response. CD289 acts as a receptor for unmethylated cytidine-phosphate-guanosine dinucleotides in bacterial DNA (CpG-DNA), playing a primary role in pathogen recognition and activation of innate immunity. Is suitable for use in immunocytochemistry on acetone fixed cells. |
Immunogen | Synthetic peptide SLKYNNLTVVPRNLPSSLEYLLLSYNRIVKL corresponding to amino acids 205-235 within the N-terminal domain of human CD289. Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Orangutan, Gibbon (100%); Monkey (97%); Marmoset (94%); Rat (90%); Mouse, Ferret, Dog, Horse, Guinea pig (84%); Hamster, Elephant, Panda, Cat, Rabbit, Pig (81%). |
Other Names | TLR9, CD289, CD289 antigen, Scri2a, Toll-like receptor 9 |
Gene, Accession # | TLR9, Gene ID: 54106 |
Catalog # | LS-C187854 |
Price | |
Order / More Info | TLR9, aa205-235 Antibody from LIFESPAN BIOSCIENCES INC. |
Product Specific References | n/a |
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