| 产品详情 |
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| Antigenic Specificity | IRG1 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human |
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| Isotype | n/a |
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| Format | Protein A purified |
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| Size | 100 ug, 200 ug |
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| Concentration | n/a |
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| Applications | ICC, IF, IHC-P, P-ELISA |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Rabbit polyclonal antibody to IRG1, which is also known as CAD. It is frequently found in the mitochondrion and is expressed in the microglia and macrophage cells. It is overexpressed in the LPS-tolerized macrophages. This protein can extensively act as a negative regulator of the toll-like receptors (TLRs)-mediated inflammatory innate response by stimulating the tumor necrosis factor alpha-induced protein TNFAIP3 expression via reactive oxygen species (ROS) in LPS-tolerized macrophages and is involved in the inhibition of the inflammatory response. |
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| Immunogen | KLH conjugated synthetic peptide derived between 33178 amino acids of human IRG1 |
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| Other Names | Immune responsive gene 1 protein homolog, Immune-responsive gene 1 protein homolog, Immunoresponsive 1 homolog (mouse), Irg1, IRG1_HUMAN, OC116, OPTB1, TCTIRC7 |
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| Gene, Accession # | Gene ID: 730249, UniProt: A6NK06 (Human) |
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| Catalog # | orb184387 |
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| Price | |
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| Order / More Info | IRG1 Antibody from BIORBYT LTD. |
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| Product Specific References | n/a |
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| 产品资料 |
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