产品详情 |
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Antigenic Specificity | UBR1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | mouse |
Isotype | n/a |
Format | peptide affinity purified |
Size | 80 µl, 400 µl |
Concentration | n/a |
Applications | WB. RUO |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The N-end rule pathway is one proteolytic pathway of the ubiquitin system. The recognition component of this pathway, encoded by this gene, binds to a destabilizing N-terminal residue of a substrate protein and participates in the formation of a substrate-linked multiubiquitin chain. This leads to the eventual degradation of the substrate protein. The protein described in this record has a RING-type zinc finger and a UBR-type zinc finger. Mutations in this gene have been associated with Johanson-Blizzard syndrome. This UBR1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 245-274 amino acids from the N-terminal region of human UBR1. |
Immunogen | Human UBR1. |
Other Names | UBR1; E3 ubiquitin-protein ligase UBR1; N-recognin-1; Ubiquitin-protein ligase E3-alpha-1; Ubiquitin-protein ligase E3-alpha-I |
Gene, Accession # | UBR1, SwissProt: Q8IWV7 |
Catalog # | abx031438 |
Price | |
Order / More Info | UBR1 Antibody from ABBEXA |
Product Specific References | n/a |
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