| 产品详情 |
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| Antigenic Specificity | GATA4 |
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| Clone | monoclonal |
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| Host Species | Mouse |
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| Reactive Species | human, mouse |
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| Isotype | IgG2b |
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| Format | ascites |
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| Size | 100 µl |
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| Concentration | n/a |
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| Applications | ELISA, WB. RUO |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | GATA binding protein 4, also known as GATA4, it is a 46 kDa member of the GATA family of zinc-finger transcription factors.Members of this family is involved in the development of cardiac hypertrophy and remodeling, and plays a critical role in regulating basal and agonist or stress induced gene expression in cardiac and smooth muscle cell types.These factors recognize the GATA motif which is present in the promoters of many genes.GATA4 contains a conserved MAPK phosphorylation site at serine 105 within the transcriptional activation domain.Serine 105 of GATA4 is phosphorylated in response to agonist stimulation through MEK 1 ERK1/2, and weakly through JNK or p38 MAPKs.GATA4 is thought to regulate genes involved in embryogenesis and in myocardial differentiation and function.Mutations in this gene have been associated with cardiac septal defects. |
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| Immunogen | Purified recombinant fragment of human GATA4 expressed in E. coli. |
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| Other Names | ASD2; VSD1; DNA binding protein GATA-GT2; GAT4; GATA binding factor-4; GATA-4; Transcription factor GATA-4; GATA binding factor 4; GATA 4; GATA4; GATA-binding factor 4; MGC126629 |
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| Gene, Accession # | Gene ID: 2626 |
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| Catalog # | abx015870 |
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| Price | |
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| Order / More Info | GATA4 Antibody from ABBEXA |
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| Product Specific References | n/a |
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