| Description | PGP9.5/UCH-L1 is a member of a gene family whose products hydrolyze small C-terminal adducts of ubiquitin to generate the ubiquitin monomer. PGP9.5 is a component of the ubiquitin system, which has a fundamental role in regulating various biological activities. PGP9.5 gene encodes two opposing enzymatic activities that affect alpha-synuclein degradation and Parkinson's disease susceptibility. Recombinant PGP9.5 protein was expressed in E. coli and purified by using conventional chromatography techniques. Alternative Names: Ubiquitin carboxyl-terminal esterase L1 Gracile axonal dystrophy protein, Ubiquitin thiolesterase protein, PGP9.5 protein, Protein gene product 9.5 protein, Neuron cytoplasmic protein 9.5 protein, Ubiquitin C terminal esterase L1 protein, Neuron cytoplasmic protein 9.5 protein, Ubiquitin carboxyl-terminal hydrolase isozyme L1 protein, PGP 9.5 protein, EC 3.4.19.12 protein, Ubiquitin thiolesterase L1., Park 5 protein, Ubiquitin thioesterase L1 protein, PGP9.5 protein, 1-223aa protein, UCH-L1 protein, Parkinson Disease 5 protein, Ubiquitin carboxyl terminal esterase L1 protein, Ubiquitin carboxyl terminal hydrolase isozyme L1 protein, UCH L1 protein, PGP95 protein, Ubiquitin C terminal hydrolase (neuron specific) protein, UCHL1 protein |
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