| 产品详情 |
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| Product Name | Ubiquitin B (UBB) (AA 153-228) protein (GST-His-S Tag) |
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| Description | Polyubiquitin-B contains 3 ubiquitin-like domains, which belongs to the ubiquitin family. Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be involved in DNA repair, Lys-11-linked is involved in ERAD and cell-cycle regulation, Lys-29-linked is involved in lysosomal degradation, Lys-33-linked is involved in kinase modification, Lys-48-linked is part in protein degradation via the proteasome, Lys-63-linked is involved in endocytosis, DNA-damage responses as well as in signaling processes leading to activation of the transcription factor NF-kappa-B. Linear polymer chains formed via attachment by the initiator Met lead to cell signaling. Ubiquitin is usually conjugated to Lys residues of target proteins, however, in rare cases, conjugation to Cys or Ser residues has been observed. When polyubiquitin is free (unanchored-polyubiquitin), it also has distinct roles, such as in activation of protein kinases, and in signaling. Synonyms: Polyubiquitin-B,UBB |
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| Size | 1 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | UBB|AL033289|Rps27a|Uba52|Ubb2|Ubc|UBC|Ubiquitin |
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| Gene, Accession, CAS # | Gene ID: 7314 |
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| Catalog # | ABIN2115323 |
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| Order / More Info | Ubiquitin B (UBB) (AA 153-228) protein (GST-His-S Tag) from ANTIBODIES-ONLINE GmbH |
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| Product Specific References | n/a |
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