| 产品详情 |
| Edit |   |
|---|
| Product Name | Cellular Retinoic Acid Binding Protein 1 (CRABP1) protein |
|---|
| Description | CRABP1 is a member of special carrier proteins for members of the vitamin A family. It is believed that CRABP1 has an essential role in retinoic acid-mediated differentiation and proliferation processes. Though, CRABP1 is structurally similar to the cellular retinol-binding proteins, it binds only retinoic acid at specific sites within the nucleus, which may contribute to vitamin A-directed differentiation in epithelial tissue. CRABP1 is constitutively expressed and is thought to have different functions in the cell than the related CRABP2. CRABP1 forms a beta-barrel structure which accommodates hydrophobic ligands in its interior.Loss of CRABP1 function as a result of hypermethylation of its promoter leads to pathogenesis of papillary thyroid carcinoma. Furthermore, frequent methylation-associated silencing of CRABP1 is linked to esophageal squamous-cell carcinoma Synonyms: Cellular retinoic acid-binding protein 1, Cellular retinoic acid-binding protein I, CRABP-I, CRABP1, RBP5, CRABP, CRABPI |
|---|
| Size | 1 mg |
|---|
| Concentration | n/a |
|---|
| Applications | n/a |
|---|
| Other Names | CRABP1|RBP1|CRBP1|RBP5|CRABP-I|cCRABP-I|CRABP|CRABPI|AI326249|Crabp-1|CrabpI|Rbp-5|CRBP-III |
|---|
| Gene, Accession, CAS # | Gene ID: 1381 |
|---|
| Catalog # | ABIN807531 |
|---|
| Price | |
|---|
| Order / More Info | Cellular Retinoic Acid Binding Protein 1 (CRABP1) protein from ANTIBODIES-ONLINE GmbH |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|