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| Product Name | Colony Stimulating Factor 2 (Granulocyte-Macrophage) (CSF2) protein |
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| Description | Human Granulocyte-Macrophage Colony Stimulating Factor GM-CSF was initially characterized as a growth factor that can support the in vitro colony formation of granulocyte-macrophage progenitors. It is produced by a number of different cell types (including activated T cells, B cells, macrophages, mast cells, endothelial cells and fibroblasts) in response to cytokine or immune and inflammatory stimuli. Besides granulocyte-macrophage progenitors, GM-CSF is also a growth factor for erythroid, megakaryocyte and eosinophil progenitors. On mature hematopoietic cells, GM-CSF is a survival factor for and activates the effector functions of granulocytes, monocytes/macrophages and eosinophils. GM-CSF has also been reported to have a functional role on non-hematopoietic cells. It can induce human endothelial cells to migrate and proliferate. Additionally, GM-CSF can also stimulate the proliferation of a number of tumor cell lines, including osteogenic sarcoma, carcinoma and adenocarcinoma cell lines. GM-CSF is species specific and human GM-CSF has no biological effects on mouse cells. |
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| Size | 1 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | CSF2|GM-CSF|GMCSF|CSF|Csfgm|Gm-CSf|MGI-IGM|Gm-csf|Gmcsf |
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| Gene, Accession, CAS # | Gene ID: 1437 |
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| Catalog # | ABIN1540366 |
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| Order / More Info | Colony Stimulating Factor 2 (Granulocyte-Macrophage) (CSF2) protein from ANTIBODIES-ONLINE GmbH |
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| Product Specific References | n/a |
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