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Product Name | Colony Stimulating Factor 2 (Granulocyte-Macrophage) (CSF2) protein |
Description | GM-CSF was initially characterized as a growth factor that can support the in vitro colony formation of granulocyte-macrophage progenitors. It is produced by a number of different cell types (including activated T cells, B cells, macrophages, mast cells, endothelial cells and fibroblasts) in response to cytokine of immune and inflammatory stimuli. Besides granulocyte-macrophage progenitors, GM-CSF is also a growth factor for erythroid, megakaryocyte and eosinophil progenitors. On mature hematopoietic, monocytes/ macrophages and eosinophils. GM-CSF has also been reported to have a functional role on non-hematopoitic cells. It can induce human endothelial cells to migrate and proliferate. Additionally, GM-CSF can also stimulate the proliferation of a number of tumor cell lines, including osteogenic sarcoma, carcinoma and adenocarcinoma cell lines. GenScript Granulocyte Macrophage Colony Stimulating Factor P. Pichia Derived (Sargramostim), human, is a single, glycosylated polypeptide chain containing 127 amino acids and having a molecular mass of about 26,000-32,000 Da, as shown in SDS-PAGE. It differs from natural human GM-CSF by a substitution of leucine at position 23 (R to L), and the carbohydrate moiety may be different from the native protein. Synonym: rHu GM-CSF, Sargramostim, Recombinant Human GM-CSF, Sargramostim. Formulation: The protein was lyophilized after extensive dialysis against 10mM Tris-HCl, pH8.5, 4% Mannitol, 1% Sucrose buffer. |
Size | 50 µg |
Concentration | n/a |
Applications | n/a |
Other Names | CSF2|GM-CSF|GMCSF|CSF|Csfgm|Gm-CSf|MGI-IGM|Gm-csf|Gmcsf |
Gene, Accession, CAS # | Gene ID: 1437 |
Catalog # | ABIN987886 |
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Order / More Info | Colony Stimulating Factor 2 (Granulocyte-Macrophage) (CSF2) protein from ANTIBODIES-ONLINE GmbH |
Product Specific References | n/a |
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