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| Product Name | L-755,507 |
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| Description | Purity >98%. L-755,507 is a partial agonist of Beta3 -adrenergic receptors (EC50 = 0.43 nM). It displays more than 440-fold selectivity for Beta3 - over Beta1 - and Beta2 -adrenoceptors (EC50 s = 580 and >10,000 nM, respectively). At 5 µM, this compound has been used to enhance CRISPR-mediated homology-directed repair efficiency by 3-fold for large fragment insertions and by 9-fold for point mutations. L-755,507 has been used to identify signaling pathways activated through Beta3 -adrenergic receptors. |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 4-[[(hexylamino)carbonyl]amino]-N-[4-[2-[[(2S)-2-hydroxy-3-(4-hydroxyphenoxy)propyl]amino]ethyl]phenyl]-benzenesulfonamide |
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| Gene, Accession, CAS # | CAS: 159182-43-1 |
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| Catalog # | LS-H8391 |
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| Order / More Info | L-755,507 from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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| 产品资料 |
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