产品详情 |
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Antigenic Specificity | GRIA2 |
Clone | monoclonal |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 |
Format | purified |
Size | 100 µg |
Concentration | 1.0 mg/ml |
Applications | ELISA, WB, FCM. RUO |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. This gene product belongs to a family of glutamate receptors that are sensitive to alpha amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA), and function as ligand-activated cation channels. These channels are assembled from 4 related subunits, Gria1-4. The subunit encoded by this gene (Gria2) is subject to RNA editing (Q/R and R/G), which is thought to render the channels impermeable to Ca (2+), and to affect the kinetic aspects of these channels in rat brain. Alternative splicing, resulting in transcript variants encoding different isoforms (flip and flop), has been noted for this gene. |
Immunogen | Purified recombinant fragment of human GRIA2 (AA: 652-807) expressed in E. Coli. |
Other Names | GluA2; GluR2; gluR-B; GluR-K2; GLURB; HBGR2 |
Gene, Accession # | GRIA2, Gene ID: 2891, SwissProt: P42262 |
Catalog # | abx010851 |
Price | |
Order / More Info | GRIA2 Antibody from ABBEXA |
Product Specific References | n/a |
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