| 产品详情 |
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| Product Name | L189 |
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| Description | Purity >95%. L189 is a competitive inhibitor of DNA ligases I, III, and IV (IC50 s = 5, 9, and 5 µM, respectively). It blocks DNA binding (Ki = 5 µM for DNA ligase I), increasing the cytotoxicity of DNA-damaging agents, including ionizing radiation. L189 preferentially inhibits the interaction of the ligase with damaged DNA, inhibiting base excision repair and non-homologous end-joining. |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 6-amino-2,3-dihydro-5-[(phenylmethylene)amino]-2-thioxo-4(1H)-pyrimidinone |
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| Gene, Accession, CAS # | CAS: 64232-83-3 |
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| Catalog # | LS-H8389 |
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| Price | |
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| Order / More Info | L189 from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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| 产品资料 |
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