| 产品详情 |
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| Antigenic Specificity | DUSP1 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse |
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| Isotype | n/a |
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| Format | affinity purified |
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| Size | 50 µl, 100 µl, 200 µl |
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| Concentration | > 1 mg/ml |
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| Applications | WB. RUO |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | DUSP1 Antibody is a Rabbit Polyclonal antibody against DUSP1. The expression of DUSP1 gene is induced in human skin fibroblasts by oxidative/heat stress and growth factors. It specifies a protein with structural features similar to members of the non-receptor-type protein-tyrosine phosphatase family, and which has significant amino-acid sequence similarity to a Tyr/Ser-protein phosphatase encoded by the late gene H1 of vaccinia virus. The bacterially expressed and purified DUSP1 protein has intrinsic phosphatase activity, and specifically inactivates mitogen-activated protein (MAP) kinase in vitro by the concomitant dephosphorylation of both its phosphothreonine and phosphotyrosine residues. Furthermore, it suppresses the activation of MAP kinase by oncogenic ras in extracts of Xenopus oocytes. Thus, DUSP1 may play an important role in the human cellular response to environmental stress as well as in the negative regulation of cellular proliferation. |
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| Immunogen | A synthetic peptide of human DUSP1. |
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| Other Names | DUSP1; dual specificity phosphatase 1; HVH1; CL100; MKP-1; PTPN10; serine/threonine specific protein phosphatase; MKP1 |
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| Gene, Accession # | DUSP1, Gene ID: 1843, SwissProt: P28562 |
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| Catalog # | abx002140 |
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| Price | |
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| Order / More Info | DUSP1 Antibody from ABBEXA |
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| Product Specific References | n/a |
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