产品详情 |
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Antigenic Specificity | MAP2K4 |
Clone | monoclonal |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 |
Format | ascites |
Size | 100 µl |
Concentration | n/a |
Applications | ELISA, WB, IHC, FCM. RUO |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This gene encodes a dual specificity protein kinase that belongs to the Ser/Thr protein kinase family.This kinase is a direct activator of MAP kinases in response to various environmental stresses or mitogenic stimuli.It has been shown to activate MAPK8/JNK1, MAPK9/JNK2, and MAPK14/p38, but not MAPK1/ERK2 or MAPK3/ERK3.This kinase is phosphorylated, and thus activated by MAP3K1/MEKK.The knockout studies in mice suggested the roles of this kinase in mediating survival signal in T cell development, as well as in the organogenesis of liver.Tissue specificity: Abundant expression is seen in the skeletal muscle.It is also widely expressed in other tissues. |
Immunogen | Purified recombinant fragment of human MAP2K4 expressed in E. coli. |
Other Names | C-Jun N-Terminal Kinase Kinase 1; Jnk-Activating Kinase 1; Mapk/Erk Kinase 4; Sapk/Erk Kinase 1; Jnkk1; Mek4; Mkk4; Prkmk4; Sek1; Serk1; Skk1; Map2K4; Dual specificity mitogen-activated protein kinase kinase 4; MEK 4; Stress-activated protein kinase kinase 1; SAP; JNKK; MAPKK4 |
Gene, Accession # | MAP2K4, Gene ID: 6416, SwissProt: P45985 |
Catalog # | abx015916 |
Price | |
Order / More Info | MAP2K4 Antibody from ABBEXA |
Product Specific References | n/a |
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