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Product Name | Adenylate Cyclase Activating Polypeptide 1 (Pituitary) (ADCYAP1) (AA 6-38) peptide |
Description | PACAP (6-38) is a potent antagonist of PACAP 38. PACAP (6-38) is much more potent and selective than PACAP (6-27) in the inhibition of PACAP-27-stimulated pituitary adenylate cyclase. Ki values for the inhibition of the enzyme were 7nM and 150 nM, respectively. PACAP (6-38) caused a small but significant (approximately 20%) inhibition of the NANC relaxation due to electrical field stimulation (1 Hz or 10 Hz for 20 s). At these frequencies PACAP (6-38) caused no inhibition of the NANC relaxation in the presence of the P2 purinoceptor antagonist pyridoxal-phosphate-6-azophenyl-2',4'-disulphonic acid (or PPADS) plus the NO-synthase blocker NG-nitro-L-arginine, in preparations pretreated with L-NOARG alone, PACAP (6-38) retained its inhibitory effect. |
Size | 5 mg |
Concentration | n/a |
Applications | n/a |
Other Names | adcyap1|GRF-PACAP|zgc:103760|xx:af217251|pac1|pacapr|pacapri|pacap|ADCYAP1|PACAP|Pacap|grf|MEDA-7|pERp1|RGD1310251|2010001M09Rik|AV064572 |
Gene, Accession, CAS # | n/a |
Catalog # | ABIN399695 |
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Order / More Info | Adenylate Cyclase Activating Polypeptide 1 (Pituitary) (ADCYAP1) (AA 6-38) peptide from ANTIBODIES-ONLINE GmbH |
Product Specific References | n/a |
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