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| Product Name | TNFSF11, 140-317aa, Human, His tag, E.coli |
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| Description | Purity: > 80% by SDS - PAGE Format: Liquid. 20mM Tris-HCl buffer (pH8.0) containing 20% glycerol, 0.1M NaCl, 1mM DTT. TNFSF11, also known as RANKL, is a member of the tumor necrosis factor (TNF) cytokine family which is a ligand for osteoprotegerin and functions as a key factor for osteoclast differentiation and activation. TNFSF11 also has a function in the immune system, where it is expressed by T helper cells and is thought to be involved in dendritic cell maturation. TNFSF11 is important in bone metabolism. This natural and necessary surface-bound molecule (also known as CD254) found on osteoblasts serves to activate osteoclasts, which are the cells involved in bone resorption. Recombinant human TNFSF11 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography. |
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| Size | 0.5mg, 100ug, 20ug |
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| Concentration | n/a |
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| Applications | SDS-PAGE |
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| Other Names | Tumor necrosis factor ligand superfamily member 11, OPGL, RANKL, TRANCE |
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| Gene, Accession, CAS # | NP 003692 |
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| Catalog # | ATGP1093 |
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| Order / More Info | TNFSF11, 140-317aa, Human, His tag, E.coli from ATGen |
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| Product Specific References | n/a |
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