| 产品详情 |
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| Product Name | Interleukin 5 Receptor, alpha (IL5RA) (AA 21-335) (Active) protein |
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| Description | Interleukin-5 Receptor Alpha (IL-5RA), also known as CD125, belongs to the Type 5 subfamily in the type I cytokine receptor family. It is composed of a ligand-specific alpha subunit and a signal-transducing beta subunit shared by the receptors for IL-3 and GM-CSF. IL-5RA is mainly expressed on eosinophils and basophils, and plays important roles in the immunobiology of these cell types. It is reported that when stimulated by IL-5, eosinophils down-regulate surface IL-5RA expression to attenuate their IL-5 responsiveness. Elevated IL-5 production may induce immune cell infiltration which leads to allergic inflammation. IL-5RA has also been reported to promote the differentiation of basophils and B cells.Synonyms: IL-5RA, CD125 |
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| Size | 1 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | MGC86517|IL5RA|il5r|cdw125|hsil5r3|gpIL-5ra|CD125|CDw125|HSIL5R3|IL5R|Il5r |
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| Gene, Accession, CAS # | Gene ID: 3568 |
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| Catalog # | ABIN2018134 |
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| Order / More Info | Interleukin 5 Receptor, alpha (IL5RA) (AA 21-335) (Active) protein from ANTIBODIES-ONLINE GmbH |
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| Product Specific References | n/a |
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