| 产品详情 |
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| Product Name | Human Amphiregulin protein |
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| Description | Amphiregulin is an EGF related growth factor and was originally isolated from the conditioned media of a PMA-treated MCF-7 human breast carcinoma cell line. It is mainly expressed numerous carcinoma cell lines and the epithelial cells of various human tissues including colon, stomach, breast, ovary, kidney, etc. Synthesized as a transmembrane protein, Amphiregulin s extracellular domain is proteolytically processed to release the mature protein. There are 6 conserved cysteine residues, which form 3 intramolecular disulfide bonds essential for biological activity. Amphiregulin signals through the EGF/TGF-a receptor, and stimulates growth of keratinocytes, epithelial cells and some fibroblasts. It also inhibits the growth of certain carcinoma cell lines. Mutations in this encoded protein are associated with a psoriasis-like skin phenotype. MW: 11.3kDa. Purity > 95% by SDS-PAGE and HPLC analyses |
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| Size | 10 ug, 50 ug, 1 mg, 100 ug, 250 ug, 500 ug |
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| Concentration | Lyophilized from a 0.2 μm filtered concentrated solution in PBS, pH 7.4. |
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| Applications | HPLC, SDS-PAGE |
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| Other Names | Human Amphiregulin protein |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | orb107683 |
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| Price | |
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| Order / More Info | Human Amphiregulin protein from BIORBYT LTD. |
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| Product Specific References | n/a |
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