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Product Name | F11 Receptor (F11R) (AA 28-238) protein (His tag) |
Description | Junctional Adhesion Molecule A (JAM-A) is a single-pass type I membrane protein that belongs to the immunoglobulin superfamily. JAM-A contains 2 Ig-like V-type (immunoglobulin-like) domains and Interacts with the ninth PDZ domain. JAM-A is localized to the tight junctions of both epithelial and endothelial cells. JAM-A seems to be involved in epithelial tight junction formation. JAM-A appears early in primordial forms of cell junctions and recruits PARD3. The association of the PARD6-PARD3 complex may prevent the interaction of PARD3 with JAM-A, thereby preventing tight junction assembly. JAM-A plays a role in regulating monocyte transmigration involved in regulating integrity of the epithelial barrier. In the case of orthoreovirus infection, JAM-A serves as receptor for the virus.Alternative Names: Junctional Adhesion Molecule A, JAM-A, Junctional Adhesion Molecule 1, JAM-1, Platelet F11 Receptor, Platelet Adhesion Molecule 1, PAM-1, CD321, F11R, JAM1, JCAM |
Size | 500 µg |
Concentration | n/a |
Applications | n/a |
Other Names | CD321|JAM|JAM1|JAMA|JCAM|KAT|PAM-1|9130004G24|AA638916|ESTM33|JAM-1|JAM-A|Jcam|Jcam1|Ly106|Jam1 |
Gene, Accession, CAS # | Gene ID: 50848 |
Catalog # | ABIN1691186 |
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Order / More Info | F11 Receptor (F11R) (AA 28-238) protein (His tag) from ANTIBODIES-ONLINE GmbH |
Product Specific References | n/a |
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