| 产品详情 |
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| Product Name | Abiraterone |
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| Description | Purity >98%. Abiraterone is the active metabolite of abiraterone acetate . Abiraterone blocks cytochrome P450 17A1 (also known as steroid 17Alpha-hydroxylase/17,20 lyase) by potently inhibiting both the 17Alpha-hydroxylase and the 17,20 lyase activities (IC50 = 18 and 17 nM, respectively). In mice as well as men, it essentially eliminates plasma testosterone while producing a 3- to 4-fold increase in plasma luteinizing hormone. In clinical trials, abiraterone improves radiographic progression-free survival and significantly delays decline in human metastatic castration-resistant prostate cancer. |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | (3Beta)-17-(3-pyridinyl)-androsta-5,16-dien-3-ol, CB-7598 |
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| Gene, Accession, CAS # | CAS: 154229-19-3 |
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| Catalog # | LS-H6376 |
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| Price | |
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| Order / More Info | Abiraterone from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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| 产品资料 |
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