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Product Name | Monoacylglycerol Lipase (MAGL) Activity Assay Kit (Fluorometric) |
Description | Monoacylglycerol Lipase (MAGL, E.C. 3.1.1.23) is an important enzyme for regulation of endocannabinoid signaling in human physiology. MAGL is a serine hydrolase that generates free fatty acid and glycerol from monoacylglycerols such as 2-arachidonoyl glycerol (2-AG), one of the principal endocannabinoids active in the nervous system. One free fatty acid that is released by MAGL activity, arachidonic acid, is a precursor for eicosanoids, a family of pro-inflammatory signaling molecules. The leftover glycerol moiety can also serve various purposes as a metabolic building block and energy source. Inhibition or inactivation of MAGL leads to 2-AG buildup, and this has myriad biological consequences. Antinociceptive effects, anti-inflammatory and |
Size | 100 assays |
Concentration | n/a |
Applications | • Measurement of monoacylglycerol lipase activity in various tissues/cells. |
Other Names | n/a |
Gene, Accession, CAS # | n/a |
Catalog # | K561-100 |
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Order / More Info | Monoacylglycerol Lipase (MAGL) Activity Assay Kit (Fluorometric) from BIOVISION, INC. |
Product Specific References | n/a |
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