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Product Name | Monoacylglycerol Lipase Inhibitor Screening Kit (Fluorometric) |
Description | Monoacylglycerol Lipase (MAGL, E.C. 3.1.1.23) is an important enzyme that regulates endocannabinoid signaling in human physiology. MAGL is a serine hydrolase that generates free fatty acid and glycerol from monoacylglycerol stores. One free fatty acid that is frequently generated by MAGL activity, arachidonic acid, is a precursor for eicosanoids, a family of pro-inflammatory signaling molecules. The glycerol moiety can also serve various purposes as a metabolic building block and energy source. Inhibition or inactivation of MAGL leads to 2-arachidonalglycerol (2-AG) buildup, and this has myriad biological consequences. Desensitization of the endocannabinoid receptors and reduced addiction withdrawal symptoms are one outcome of MAGL inhibiti |
Size | 100 assays |
Concentration | n/a |
Applications | • Screening for inhibitors of human MAGL enzyme |
Other Names | n/a |
Gene, Accession, CAS # | n/a |
Catalog # | K474-100 |
Price | |
Order / More Info | Monoacylglycerol Lipase Inhibitor Screening Kit (Fluorometric) from BIOVISION, INC. |
Product Specific References | n/a |
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